Diel post-translational regulation of plant cell processes

Using quantitative label-free proteomics, we aim to identify and characterize diel post-translational modification (PTM)-regulated plant cell processes. This work is  currently being undertaken using the model plant Arabidopsis thaliana. 

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Targeted characterization of PTM modifying enzymes

Despite the identification of 1000s of PTM modified proteins, there remains a large gap in our understanding of which PTM modifying enzymes specifically catalyze which PTM events. Using a suite of functional genomic tools in combination with targeted proteomics, biochemistry and molecular biology our research efforts look to connect PTM modifying enzymes with specific substrates.