Diurnal post-translational regulation of plant cell processes
Using quantitative label-free proteomics, we aim to identify and characterize diurnal post-translational modification (PTM)-regulated plant cell processes. This work is currently being undertaken using the model plant Arabidopsis thaliana.
Targeted characterization of PTM modifying enzymes
Despite the identification of 1000s of PTM modified proteins, there remains a large gap in our understanding of which PTM modifying enzymes specifically catalyze which PTM events. Using a suite of functional genomic tools in combination with targeted proteomics, biochemistry and molecular biology our research efforts look to connect PTM modifying enzymes with specific substrates.