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Functional Genomics & Plant Cell Regulation |
Understanding plant life, one protein at a time
We use cutting-edge proteomics and functional genomics to uncover how plant cells regulate themselves — knowledge that points the way to more resilient crops and a more food-secure world.
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Plants regulate cellular processes based on the presence or absence of light through a combination of anticipatory (circadian) and reactive (light responsive) mechanisms. Together, these mechanisms allow plants to dynamically adapt to their daily environment as well as signal developmental events (e.g. flowering). To date, the extent to which diel plant cell regulation is controlled by changes in protein abundance and/or post-translational protein modifications (PTMs) remains poorly understood.
PTMs are central to properly functioning cells. They represent fast-acting, fine-tuning mechanisms for regulating protein activities, changes in sub-cellular localization and protein-protein interactions, amongst others, collectively resulting in diverse biological outcomes. Protein phosphorylation and protein acetylation are two of the the most abundant PTMs identified to date. Given this, our work is focused on identifying and characterizing plant cell processes regulated by these PTMs.
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Khodabocus, Li, Mehta and Uhrig 2020
Khodabocus, Li, Mehta and Uhrig 2020
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