Selected Publications
2018
15. Labandera AM, Uhrig RG, Colville K, Moorhead GB, Ng KKS. Structural basis for the preference of the Arabidopsis thaliana phosphatase RLPH2 for tyrosine-phosphorylated substrates. Science Signalling. Apr 3;11(524). doi: 10.1126/scisignal.aan8804.
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2017
14. Hartl M, Füßl M, Boersema PJ, Jost JO, Kramer K, Bakirbas A, Sindlinger J, Plöchinger M, Leister D, Uhrig G, Moorhead GB, Cox J, Salvucci ME, Schwarzer D, Mann M, Finkemeier I. Lysine acetylome profiling uncovers novel histone deacetylase substrate proteins in Arabidopsis. Molecular Systems Biology. Oct 23;13(10):949. doi: 10.15252/msb.20177819.
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13. Uhrig RG, Schlapfer P, Mehta D, Hirsch-Hoffmann M and Gruissem W. Genome-scale analysis of regulatory protein acetylation enzymes from photosynthetic eukaryotes. BMC Genomics. 2017. Jul 5;18(1):514. doi: 10.1186/s12864-017-3894-0.
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12. Uhrig RG and Moorhead GB. AtSLP2 is an intronless protein phosphatase that co-expresses with intronless mitochondrial pentatricopeptide repeat (PPR) and tetratricopeptide (TPR) protein encoding genes. Plant Signaling and Behavior. 2017. doi: 10.1080/15592324.2017.1307493.
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11. Graf A*, Coman D*, Uhrig RG*, Walsh S, Flis A, Stitt M and Gruissem W. Parallel analysis of Arabidopsis circadian clock mutants reveals different scales of transcriptome and proteome regulation. Open Biology. Mar;7(3). doi: 10.1098/rsob.160333.
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10. Uhrig RG, Labandera A-M, Tang L-Y, Sieben NA, Goudreault M, Yeung ECT, Gingras A-C, Samuel M and Moorhead GB. Activation of mitochondrial protein phosphatase SLP2 by MIA40 regulates seed germination. Plant Physiology. Feb;173(2):956-969. doi: 10.1104/pp.16.01641.
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2016
9. Uhrig RG*, Labandera* A-M, Muhammad J, Samuel M and Moorhead GB. Rhizobiale-like phosphatase 2 from Arabidopsis thaliana is a novel phospho-tyrosine specific PPP-family protein phosphatase. Journal of Biological Chemistry. 291(11):5926-34. doi: 10.1074/jbc.M115.683656.
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2015
8. Kerk D, Silver DM, Uhrig RG and Moorhead GB. “PP2C7s”, Genes most highly elaborated in photosynthetic organisms, reveal the bacterial origin and stepwise evolution of PPM/PP2C protein phosphatases. PLoS One. Aug 4;10(8):e0132863. doi: 10.1371/journal.pone.0132863.
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2013
7. Uhrig RG*, Kerk D* and Moorhead GB. Evolution of bacterial-like PPP protein phosphatases in photosynthetic eukaryotes features ancestral mitochondrial or archaeal origin overlaid by lateral gene transfer. Plant Physiology. 163(4):1829-43. doi: 10.1104/pp.113.224378.
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6. Uhrig RG, Labandera A-M and Moorhead GB. Arabidopsis PPP serine / threonine protein phosphatases: many targets but few engines. Trends in Plant Science. 18(9): 505-13. doi: 10.1016/j.tplants.2013.05.004.
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5. Uhrig RG and Moorhead GB. Plant Proteomics: current status and future prospects. Journal of Proteomics. 88:34-6. doi: 10.1016/j.jprot.2013.01.018.
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4. Skene-Arnold TD, Luu HA, Uhrig RG, De Wever V, Nimick M, Maynes J, Fong A, James MN, Trinkle-Mulcahy L, Moorhead GB, Holmes CF. Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins. Biochemical Journal. Feb 1;449(3):649-59. doi: 10.1042/BJ20120506.
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2012
3. Tran HT, Uhrig RG, Nimick M and Moorhead GB. Interfacing protein lysine acetylation and protein phosphorylation: Ancient modifications meet ancient proteins. Plant Signaling and Behavior. Aug;7(8):901-3. doi: 10.4161/psb.20704.
Download
2. Tran HT*, Nimick M*, Uhrig RG*, Templeton G, Morrice N, Gourlay R, Delong A and Moorhead GB. Arabidopsis thaliana Histone Deacetylase 14 (Hda14) is an α-Tubulin Deacetylase that associates with Pp2a and enriches in the microtubule fraction with the putative Histone Acetyltransferase Elp3. The Plant Journal. Jul;71(2):263-72. doi: 10.1111/j.1365-313X.2012.04984.x.
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2011
1. Uhrig RG and Moorhead GB. Two ancient bacterial-like PPP family phosphatases from Arabidopsis thaliana are highly conserved plant proteins that possess unique properties. Plant Physiology. Dec;157(4):1778-92. doi: 10.1104/pp.111.182493.
Download
15. Labandera AM, Uhrig RG, Colville K, Moorhead GB, Ng KKS. Structural basis for the preference of the Arabidopsis thaliana phosphatase RLPH2 for tyrosine-phosphorylated substrates. Science Signalling. Apr 3;11(524). doi: 10.1126/scisignal.aan8804.
Download
2017
14. Hartl M, Füßl M, Boersema PJ, Jost JO, Kramer K, Bakirbas A, Sindlinger J, Plöchinger M, Leister D, Uhrig G, Moorhead GB, Cox J, Salvucci ME, Schwarzer D, Mann M, Finkemeier I. Lysine acetylome profiling uncovers novel histone deacetylase substrate proteins in Arabidopsis. Molecular Systems Biology. Oct 23;13(10):949. doi: 10.15252/msb.20177819.
Download
13. Uhrig RG, Schlapfer P, Mehta D, Hirsch-Hoffmann M and Gruissem W. Genome-scale analysis of regulatory protein acetylation enzymes from photosynthetic eukaryotes. BMC Genomics. 2017. Jul 5;18(1):514. doi: 10.1186/s12864-017-3894-0.
Download
12. Uhrig RG and Moorhead GB. AtSLP2 is an intronless protein phosphatase that co-expresses with intronless mitochondrial pentatricopeptide repeat (PPR) and tetratricopeptide (TPR) protein encoding genes. Plant Signaling and Behavior. 2017. doi: 10.1080/15592324.2017.1307493.
Download
11. Graf A*, Coman D*, Uhrig RG*, Walsh S, Flis A, Stitt M and Gruissem W. Parallel analysis of Arabidopsis circadian clock mutants reveals different scales of transcriptome and proteome regulation. Open Biology. Mar;7(3). doi: 10.1098/rsob.160333.
Download
10. Uhrig RG, Labandera A-M, Tang L-Y, Sieben NA, Goudreault M, Yeung ECT, Gingras A-C, Samuel M and Moorhead GB. Activation of mitochondrial protein phosphatase SLP2 by MIA40 regulates seed germination. Plant Physiology. Feb;173(2):956-969. doi: 10.1104/pp.16.01641.
Download
2016
9. Uhrig RG*, Labandera* A-M, Muhammad J, Samuel M and Moorhead GB. Rhizobiale-like phosphatase 2 from Arabidopsis thaliana is a novel phospho-tyrosine specific PPP-family protein phosphatase. Journal of Biological Chemistry. 291(11):5926-34. doi: 10.1074/jbc.M115.683656.
Download
2015
8. Kerk D, Silver DM, Uhrig RG and Moorhead GB. “PP2C7s”, Genes most highly elaborated in photosynthetic organisms, reveal the bacterial origin and stepwise evolution of PPM/PP2C protein phosphatases. PLoS One. Aug 4;10(8):e0132863. doi: 10.1371/journal.pone.0132863.
Download
2013
7. Uhrig RG*, Kerk D* and Moorhead GB. Evolution of bacterial-like PPP protein phosphatases in photosynthetic eukaryotes features ancestral mitochondrial or archaeal origin overlaid by lateral gene transfer. Plant Physiology. 163(4):1829-43. doi: 10.1104/pp.113.224378.
Download
6. Uhrig RG, Labandera A-M and Moorhead GB. Arabidopsis PPP serine / threonine protein phosphatases: many targets but few engines. Trends in Plant Science. 18(9): 505-13. doi: 10.1016/j.tplants.2013.05.004.
Download
5. Uhrig RG and Moorhead GB. Plant Proteomics: current status and future prospects. Journal of Proteomics. 88:34-6. doi: 10.1016/j.jprot.2013.01.018.
Download
4. Skene-Arnold TD, Luu HA, Uhrig RG, De Wever V, Nimick M, Maynes J, Fong A, James MN, Trinkle-Mulcahy L, Moorhead GB, Holmes CF. Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins. Biochemical Journal. Feb 1;449(3):649-59. doi: 10.1042/BJ20120506.
Download
2012
3. Tran HT, Uhrig RG, Nimick M and Moorhead GB. Interfacing protein lysine acetylation and protein phosphorylation: Ancient modifications meet ancient proteins. Plant Signaling and Behavior. Aug;7(8):901-3. doi: 10.4161/psb.20704.
Download
2. Tran HT*, Nimick M*, Uhrig RG*, Templeton G, Morrice N, Gourlay R, Delong A and Moorhead GB. Arabidopsis thaliana Histone Deacetylase 14 (Hda14) is an α-Tubulin Deacetylase that associates with Pp2a and enriches in the microtubule fraction with the putative Histone Acetyltransferase Elp3. The Plant Journal. Jul;71(2):263-72. doi: 10.1111/j.1365-313X.2012.04984.x.
Download
2011
1. Uhrig RG and Moorhead GB. Two ancient bacterial-like PPP family phosphatases from Arabidopsis thaliana are highly conserved plant proteins that possess unique properties. Plant Physiology. Dec;157(4):1778-92. doi: 10.1104/pp.111.182493.
Download